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Special Notices (update date descending order)

Important Note When Upgrading to macOS 27 (Golden Gate)

Category: Special Notices
Also available: 日本語 (Japan)

After upgrading to macOS 27, your LDK dongle (HardKey license) may not be recognized, and IMC may fall back to a software key license instead. This happens because Rosetta 2 - the compatibility layer that runs Intel-built software on Apple Silicon - is not installed by default on macOS 27.

If your dongle is not recognized, install Rosetta 2 as follows:

  1. Open the Terminal app
  2. Run the following command:
    softwareupdate --install-rosetta --agree-to-license
  3. Restart IMC
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IMC Version 9.3.0 Release Notes

Category: IMC Release News
Also available: 日本語 (Japan)

The latest IMC Version 9.3.0 installer for Windows has been released.

The latest IMC Version 9.3.0 installer for macOS has been released.

  • macOS 13 (Ventura), 14 (Sonoma), 15 (Sequoia), 26 (Tahoe, SoftKey License Only)
  • Windows 11

New Features, Feature Changes/Improvements, Bug Fixes

New Features

  • Cloning Workbench (beta)
  • Integrated (Multiple) Ligation (beta)
  • Ligation Simulation (beta)
  • Graphical Tools for Ligation (beta)
  • New Plasmid Map (beta)
  • Fragment Assembly Primer Design (beta)
    • Golden Gate Assembly, etc.
  • Construct Canvas (beta)
  • DNA Fragment Assembly Workbench
  • Added FBA and FVA to the Metabolic Pathway feature (beta)
  • FBA/FVA results can now be shown as a series graph overlay on the Metabolic Pathway Canvas (beta)
  • Added a sample Genome Scale Model install option
    • If you do not need the Genome Scale Model, please delete the model file.

Feature Changes/Improvements

  • Significantly reduced IMC startup time
  • You can now choose to show or hide each button individually, and change its display order within its group.
  • Slightly adjusted the layout of the Cloning Workbench.
  • Added the New Plasmid Map feature.
  • Improved the Primer Design feature for Fragment Assembly.

Bug Fixes

  • Fixed an issue where the state transitions of the Tool buttons on the Top, Bottom, Left, and Right of the Main Window were incorrect.
  • Fixed several minor bugs in IMC.
Hits: 2663

New Server Deployment of www.insilico-biology.com site

Category: Site
Also available: 日本語 (Japan)

Due to issues that occurred earlier this week, we have been working on migrating our website to a new server. As the restoration of functionality has been largely completed, the site is now back online on the new server as of today.

We acknowledge that this may have caused inconvenience for some users.

www.insilico-biology.com

in silico biology, Inc.

Hits: 12319

Notice of Service Suspension and Migration to a New Website for www.insilico-biology.com

Category: Special Notices
Also available: 日本語 (Japan)

We have confirmed that our website (www.insilico-biology.com) is currently unable to start properly due to a system failure.

As this issue coincides with the scheduled renewal of our server environment, we have decided not to restore the existing site and will instead proceed with the migration to a new server and the construction of a new website. Accordingly, www.insilico-biology.com will remain inaccessible for the time being.

This website has served as an important resource for IMC product technical information and help documentation. Until the new site is ready, we will temporarily provide selected technical information on our main company website (www.insilicobiology.co.jp (insilicobiology.co.jp in Bing)).

We sincerely apologize for any inconvenience this may cause. We are working to prepare the new site and appreciate your patience until its release.

Sincerely, In Silico Biology, Inc.

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